Uro-oncology Archives - Gerry Collins Urology https://d.ambeego.com/category/uro-oncology/ Expert Urology. Clear Decisions. Healthier Future Mon, 23 Feb 2026 08:00:24 +0000 en-US hourly 1 https://wordpress.org/?v=7.0.1 https://d.ambeego.com/wp-content/uploads/2026/03/cropped-gv-logo-32x32.png Uro-oncology Archives - Gerry Collins Urology https://d.ambeego.com/category/uro-oncology/ 32 32 Testicular Cancer: A Guide to Early Detection and Specialist Care https://d.ambeego.com/testicular-cancer/ https://d.ambeego.com/testicular-cancer/#respond Mon, 23 Feb 2026 07:51:42 +0000 https://gerry-collins-urology-wp-tkeapw-d74642-23-88-63-91.traefik.me/?p=2049 Testicular cancer is a condition where malignant cells develop in the tissues of one or both testicles. These oval-shaped organs, housed within the scrotum, are responsible for producing sperm and the primary male sex hormone, testosterone. While it is relatively rare compared to other urological conditions, it remains the most common cancer affecting men between the ages of 15 and 49 in the UK. The disease typically begins in the germ cells, which are the cells responsible for creating sperm. Most cases are highly treatable and curable, especially when identified in the early stages. However, because it often affects younger men who may not be accustomed to regular health screenings, awareness and prompt action are vital. Relevant Fact: In the United Kingdom, approximately 2,400 new cases of testicular cancer are diagnosed every year. Despite this, it has one of the highest survival rates of any cancer, with more than 96% of men surviving for 10 years or more after diagnosis. Symptoms The most common sign of testicular cancer is a painless lump or swelling. However, several other indicators should prompt a consultation: Causes & Risk Factors While the exact cause of testicular cancer remains unknown, several factors are known to increase a man’s risk: The Solution: Treatment pathways The primary objective of treatment is to remove the cancer while preserving quality of life and future fertility. Surgical Intervention:The standard treatment is an orchidectomy, which is the surgical removal of the affected testicle. This is usually performed through an incision in the groin. To address the aesthetic and psychological impact, Mr Collins offers the option of a prosthetic (artificial) testicle, which can be inserted during the same procedure to maintain a natural appearance. Medical Management:Following surgery, the removed tissue is analysed to determine if it is a seminoma or a non-seminoma. Depending on the stage and type: Fertility Preservation:Because treatments can affect sperm production, Mr Collins ensures that “Sperm Banking” is discussed and arranged before any intensive treatment begins, providing peace of mind for future family planning. How to Prevent? There is no known way to prevent testicular cancer, as it is not linked to lifestyle choices like smoking or diet. Therefore, the focus is entirely on early detection through self-examination. FAQs Based in Manchester and Cheshire, Mr Gerald Collins is currently accepting private consultations for the assessment of kidney masses, haematuria, and general urological concerns. With 29 years of experience, he provides the clarity and expertise needed to move from uncertainty to a confident treatment plan.

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Testicular cancer is a condition where malignant cells develop in the tissues of one or both testicles. These oval-shaped organs, housed within the scrotum, are responsible for producing sperm and the primary male sex hormone, testosterone. While it is relatively rare compared to other urological conditions, it remains the most common cancer affecting men between the ages of 15 and 49 in the UK.

The disease typically begins in the germ cells, which are the cells responsible for creating sperm. Most cases are highly treatable and curable, especially when identified in the early stages. However, because it often affects younger men who may not be accustomed to regular health screenings, awareness and prompt action are vital.

Relevant Fact:

In the United Kingdom, approximately 2,400 new cases of testicular cancer are diagnosed every year. Despite this, it has one of the highest survival rates of any cancer, with more than 96% of men surviving for 10 years or more after diagnosis.

Symptoms

The most common sign of testicular cancer is a painless lump or swelling. However, several other indicators should prompt a consultation:

  • A Palpable Lump: A small, hard lump, often described as feeling like a pea or a grain of rice, located on the front or side of the testicle.
  • Changes in Texture: A testicle that feels unusually firm, hard, or has changed its regular consistency.
  • Heaviness: A dragging sensation or a feeling of increased weight in the scrotum.
  • Size Discrepancy: While it is normal for one testicle to be slightly larger or hang lower than the other, a significant or sudden change in size should be noted.
  • Ache or Discomfort: A dull ache in the lower abdomen or the groin area.
  • Late Stage Signs: If the cancer spreads to the lymph nodes or lungs, symptoms may include back pain, a persistent cough, or shortness of breath.
gerry collins

Mr Collins Approach

Having conducted MD research at the Mayo Clinic and Edinburgh University, Mr Collins focuses on what is clinically significant for the individual. This means carefully staging the disease and discussing the nuances of treatment, such as the timing of surgery and the preservation of long-term health, rather than rushing a generic plan. His role as the European Editor of The Prostate Journal at Harvard ensures that his practice is always at the forefront of global oncological research.

Causes & Risk Factors

While the exact cause of testicular cancer remains unknown, several factors are known to increase a man’s risk:

  • Undescended Testicles (Cryptorchidism)

    This is the most significant risk factor. Men born with testicles that did not naturally descend into the scrotum are at a higher risk, even if they had surgery as a child to correct it.

  • Ethnicity

    Statistical data shows that testicular cancer is more common in white men than in men of other ethnic backgrounds.

  • Family History

    Having a father or brother who has had the disease increases individual risk.

  • Previous Diagnosis

    Men who have previously had cancer in one testicle have an increased risk of developing it in the other.

  • Specific Conditions

    Conditions such as HIV or certain abnormal cell developments (Carcinoma in situ) within the testicle can heighten risk levels.

The Solution: Treatment pathways

The primary objective of treatment is to remove the cancer while preserving quality of life and future fertility.

Surgical Intervention:
The standard treatment is an orchidectomy, which is the surgical removal of the affected testicle. This is usually performed through an incision in the groin. To address the aesthetic and psychological impact, Mr Collins offers the option of a prosthetic (artificial) testicle, which can be inserted during the same procedure to maintain a natural appearance.

Medical Management:
Following surgery, the removed tissue is analysed to determine if it is a seminoma or a non-seminoma. Depending on the stage and type:

  • Surveillance: For low-risk cases, regular scans and blood tests are used to monitor the patient without further immediate treatment.
  • Chemotherapy: Used to kill any remaining cancer cells and reduce the risk of recurrence.
  • Radiotherapy: Often used for seminomas that have spread to the lymph nodes.

Fertility Preservation:
Because treatments can affect sperm production, Mr Collins ensures that “Sperm Banking” is discussed and arranged before any intensive treatment begins, providing peace of mind for future family planning.

How to Prevent?

There is no known way to prevent testicular cancer, as it is not linked to lifestyle choices like smoking or diet. Therefore, the focus is entirely on early detection through self-examination.

  • The Monthly Check: You should examine your testicles once a month.
  • The Best Time: Perform the check after a warm bath or shower. The heat relaxes the scrotum, making it much easier to feel for anything unusual.
  • The Technique: Use both hands to roll each testicle between your thumb and fingers. Get to know what is “normal” for you.
  • Identify the Epididymis: Do not be alarmed by a soft, coiled tube at the back of the testicle. This is the epididymis, which stores sperm, and it is a normal part of your anatomy.
  • Act Quickly: If you find a lump, do not wait for it to go away. Most lumps are benign cysts or swollen veins (varicoceles), but only a specialist can provide the certainty required.

FAQs

Will I still be able to have sex and get erections?

Yes. Removing one testicle does not typically affect your ability to have an erection or perform sexually. The remaining healthy testicle usually produces enough testosterone to compensate.

Will it affect my ability to have children?

Having one testicle removed generally does not cause infertility, as the remaining one continues to produce sperm. However, if chemotherapy or radiotherapy is required, fertility can be affected. This is why we prioritise sperm banking before these treatments begin.

Is the surgery painful?

The procedure is performed under general anaesthesia. Post-operative discomfort is usually well managed with standard pain relief, and most men return to light activities within a week or two.

Is it definitely cancer if I find a lump?

No. In fact, most lumps found in the scrotum are not cancerous. They are often harmless cysts or fluid collections. However, because you cannot tell

Based in Manchester and Cheshire, Mr Gerald Collins is currently accepting private consultations for the assessment of kidney masses, haematuria, and general urological concerns. With 29 years of experience, he provides the clarity and expertise needed to move from uncertainty to a confident treatment plan.

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Kidney Cancer: Understanding the Diagnosis and Your Path Forward https://d.ambeego.com/kidney-cancer/ https://d.ambeego.com/kidney-cancer/#respond Mon, 23 Feb 2026 06:37:29 +0000 https://gerry-collins-urology-wp-tkeapw-d74642-23-88-63-91.traefik.me/?p=2043 The kidneys are two bean-shaped organs located near the middle of your back, just below the ribs. Their primary role is to act as the body’s sophisticated filtration system, processing waste products from the blood and converting them into urine. Kidney cancer, also known as renal cancer, occurs when abnormal cells within these organs begin to divide and grow in an uncontrolled manner. In the UK, the most common form of the disease is Renal Cell Carcinoma (RCC), which accounts for approximately 80% of cases. While a diagnosis can feel overwhelming, advancements in imaging and surgical techniques mean that many kidney tumours are now caught early, often incidentally during scans for unrelated conditions. At this stage, the disease is highly manageable and often curable. Relevant Fact: Every year, over 9,000 people in the UK are diagnosed with kidney cancer. Due to the increased use of modern imaging like CT scans, many of these cases are discovered when the tumours are small and have not yet caused any outward symptoms. Symptoms The most significant indicator of bladder cancer is haematuria, which is the medical term for blood in the uIn its earliest stages, kidney cancer rarely presents obvious signs. However, as a tumour grows, certain “red flags” may emerge. You should seek a consultation if you notice: If you notice blood in your urine, it is vital to have it investigated promptly. While it can be caused by infections or stones, it is a primary indicator that requires professional urological assessment. Causes & Risk Factors While the exact cause of most kidney cancers remains unclear, certain factors can increase your risk: The Solution: Treatment pathways The treatment for kidney cancer is highly personalised, depending on the stage and grade of the tumour. Mr Collins specialises in navigating these complex decisions: Surgical Pathways: Medical and Minimally Invasive Pathways: How to Prevent? While you cannot change your genetics, you can take active steps to lower your risk: FAQs Based in Manchester and Cheshire, Mr Gerald Collins is currently accepting private consultations for the assessment of kidney masses, haematuria, and general urological concerns. With 29 years of experience, he provides the clarity and expertise needed to move from uncertainty to a confident treatment plan.

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The kidneys are two bean-shaped organs located near the middle of your back, just below the ribs. Their primary role is to act as the body’s sophisticated filtration system, processing waste products from the blood and converting them into urine. Kidney cancer, also known as renal cancer, occurs when abnormal cells within these organs begin to divide and grow in an uncontrolled manner.

In the UK, the most common form of the disease is Renal Cell Carcinoma (RCC), which accounts for approximately 80% of cases. While a diagnosis can feel overwhelming, advancements in imaging and surgical techniques mean that many kidney tumours are now caught early, often incidentally during scans for unrelated conditions. At this stage, the disease is highly manageable and often curable.

Relevant Fact:

Every year, over 9,000 people in the UK are diagnosed with kidney cancer. Due to the increased use of modern imaging like CT scans, many of these cases are discovered when the tumours are small and have not yet caused any outward symptoms.

Symptoms

The most significant indicator of bladder cancer is haematuria, which is the medical term for blood in the uIn its earliest stages, kidney cancer rarely presents obvious signs. However, as a tumour grows, certain “red flags” may emerge. You should seek a consultation if you notice:

  • Haematuria: Blood in your urine, which may appear pink, red, or the colour of cola.
  • Persistent Pain: A dull ache or sharp pain in your side or back (flank) that does not go away.
  • A Palpable Mass: A lump or swelling in the kidney area, under the ribs, or occasionally in the neck.
  • Systemic Symptoms: Unexplained weight loss, a persistent high temperature, night sweats, or extreme fatigue.

If you notice blood in your urine, it is vital to have it investigated promptly. While it can be caused by infections or stones, it is a primary indicator that requires professional urological assessment.

gerry collins

Mr. Collins Approach

Mr Gerald Collins brings nearly three decades of clinical experience to the management of kidney cancer.
His philosophy is rooted in the “Science and Art” of healing, a perspective shaped by his fifth-generation medical pedigree and his time conducting research at Edinburgh University and the Mayo Clinic in the USA.

Causes & Risk Factors

While the exact cause of most kidney cancers remains unclear, certain factors can increase your risk:

  • Smoking

    Tobacco use significantly raises the risk, though this decreases after quitting.

  • Age & Gender

    The disease is more common in men and those over the age of 60.

  • Obesity

    Being overweight is a known contributor to renal cell changes.

  • Genetic Factors

    Rare inherited conditions such as von Hippel-Lindau (VHL) disease or Birt-Hogg-Dube syndrome can predispose individuals to kidney tumours.

  • Environmental Exposure

    Long-term exposure to materials like asbestos or cadmium may play a role.

  • Hypertension

    High blood pressure is consistently linked to an increased incidence of kidney cancer.

The Solution: Treatment pathways

The treatment for kidney cancer is highly personalised, depending on the stage and grade of the tumour. Mr Collins specialises in navigating these complex decisions:

Surgical Pathways:

  • Partial Nephrectomy: Whenever possible, we aim to remove only the tumour, preserving as much healthy kidney tissue as possible. This is often the preferred route for smaller masses.
  • Radical Nephrectomy: In cases where the tumour is large or centrally located, the entire kidney may need to be removed. The body can function perfectly well with one healthy kidney.

Medical and Minimally Invasive Pathways:

  • Active Surveillance: For very small, slow-growing tumours in older patients or those with other health concerns, monitoring the mass with regular scans may be the safest “measured intervention.”
  • Ablation Therapies: For patients unsuitable for surgery, techniques like Cryotherapy (freezing) or Radiofrequency Ablation (using heat) can destroy cancer cells.
  • Advanced Therapies: For cancer that has spread beyond the kidney (metastatic), modern treatments include immunotherapy and targeted drug therapies, which have revolutionised outcomes in recent years.

How to Prevent?

While you cannot change your genetics, you can take active steps to lower your risk:

  1. Stop Smoking: This is the single most impactful change you can make for urological health.
  2. Manage Your Blood Pressure: Have your blood pressure checked regularly by your GP. If it is high, manage it through a combination of diet, exercise, and medication.
  3. Maintain a Healthy Weight: A diet rich in fruits and vegetables, combined with at least 30 minutes of exercise most days, helps regulate the hormonal and inflammatory markers linked to kidney cancer.
  4. Stay Hydrated: While hydration does not directly prevent cancer, it supports overall kidney function and health.
kidney cancer

FAQs

Can I live a normal life with only one kidney?

Yes. Most people lead perfectly healthy, full lives with one kidney. The remaining kidney usually increases in size slightly to take over the work of both.

Is a kidney cyst always cancer?

No. Kidney cysts are very common, especially as we age. We use the Bosniak classification system to grade these cysts. Simple cysts (Category I) are almost never cancerous, while complex cysts (Category IV) require surgical attention.

Is blood in the pee always a sign of cancer?

Not necessarily. It can be caused by a urinary tract infection (UTI), kidney stones, or an enlarged prostate. However, visible blood in the urine must always be investigated by a urologist to rule out serious underlying causes.

Why was my kidney cancer found “by accident”?

Many kidney tumours are “incidentalomas,” meaning they are found during an ultrasound or CT scan for something else, such as gallstones or back pain. This is actually a positive outcome, as it usually means the cancer is caught at an early, highly treatable stage.

Based in Manchester and Cheshire, Mr Gerald Collins is currently accepting private consultations for the assessment of kidney masses, haematuria, and general urological concerns. With 29 years of experience, he provides the clarity and expertise needed to move from uncertainty to a confident treatment plan.

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Bladder Cancer: Understanding the Risks, the Signs, and the Strategy https://d.ambeego.com/bladder-cancer/ https://d.ambeego.com/bladder-cancer/#respond Mon, 23 Feb 2026 06:06:24 +0000 https://gerry-collins-urology-wp-tkeapw-d74642-23-88-63-91.traefik.me/?p=2040 The bladder is a hollow, muscular organ located in the lower abdomen, responsible for the storage of urine. Bladder cancer occurs when the cells lining this organ begin to grow uncontrollably, forming a tumour. Most cases originate in the urothelial cells, which are the same cells found in the kidneys and ureters. In the UK, approximately 10,000 people are diagnosed with bladder cancer every year. While it is a serious diagnosis, urological medicine has advanced significantly. When identified early, the condition is highly treatable, but it requires a strategic, long-term surveillance plan because of its tendency to recur. Relevant Fact: Approximately 8 out of 10 (80%) of bladder cancers in the UK are diagnosed at an early stage, when the cancer is confined to the inner lining of the bladder and is most responsive to treatment. Symptoms The most significant indicator of bladder cancer is haematuria, which is the medical term for blood in the urine. It is often painless and may not happen every day. You should seek an urgent GP appointment or contact NHS 111 if you notice: In more advanced cases, patients may experience pain in the lower tummy or back, unexplained weight loss, or a persistent feeling of tiredness. If the cancer has spread beyond the bladder, bone pain or swelling in the legs can also occur. Causes & Risk Factors Several factors can influence the development of bladder cancer. Understanding these is vital for both prevention and diagnosis: The Solution: Treatment pathways The treatment strategy depends on whether the cancer is non-muscle-invasive (early) or muscle-invasive (advanced). Diagnostic Pathway Diagnosis typically begins with a cystoscopy, where a thin camera is passed into the bladder, and a CT scan. If an abnormality is found, further staging is sometimes performed with an MR scan of the bladder area. Usually then a procedure called TURBT (Transurethral Resection of a Bladder Tumour) is performed. This is both a diagnostic tool, providing a biopsy to determine the grade and stage, and often the first step in treatment. Treatment Options How to Prevent? While some risk factors like age cannot be changed, you can take proactive steps to protect your bladder health: FAQs

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The bladder is a hollow, muscular organ located in the lower abdomen, responsible for the storage of urine. Bladder cancer occurs when the cells lining this organ begin to grow uncontrollably, forming a tumour. Most cases originate in the urothelial cells, which are the same cells found in the kidneys and ureters.

In the UK, approximately 10,000 people are diagnosed with bladder cancer every year. While it is a serious diagnosis, urological medicine has advanced significantly. When identified early, the condition is highly treatable, but it requires a strategic, long-term surveillance plan because of its tendency to recur.

Relevant Fact:

Approximately 8 out of 10 (80%) of bladder cancers in the UK are diagnosed at an early stage, when the cancer is confined to the inner lining of the bladder and is most responsive to treatment.

Symptoms

The most significant indicator of bladder cancer is haematuria, which is the medical term for blood in the urine. It is often painless and may not happen every day.

You should seek an urgent GP appointment or contact NHS 111 if you notice:

  • Visible blood in your pee, which may appear bright red, pink, or even a dark brown cola colour.
  • Blood that appears once and then disappears, it still requires investigation.
  • Frequent urinary tract infections (UTIs) that do not seem to clear with standard treatment.
  • A sudden or urgent need to urinate, even when the bladder is not full.
  • A burning sensation or pain during urination.

In more advanced cases, patients may experience pain in the lower tummy or back, unexplained weight loss, or a persistent feeling of tiredness. If the cancer has spread beyond the bladder, bone pain or swelling in the legs can also occur.

gerry collins

Mr. Collins Approach

With 29 years of experience, Mr Gerry Collins approaches urology as a combination of rigorous science and delicate art.

He believes the greatest advantage a patient can have is a surgeon who listens, filtering out the clinical noise to focus on what is significant for the individual. His role as the European Editor of The Prostate Journal (Harvard) and his extensive research portfolio (over 100 publications) ensure his patients benefit from the latest global evidence, delivered with the nuance of three decades of surgical practice.

Causes & Risk Factors

Several factors can influence the development of bladder cancer. Understanding these is vital for both prevention and diagnosis:

  • Smoking

    This is the primary cause in about 40 percent of cases. Harmful chemicals from tobacco enter the bloodstream, are filtered by the kidneys, and sit in the bladder, damaging the lining.

  • Age & Gender

    The risk increases as you age, with most diagnoses occurring in those over 55. It is also significantly more common in men than women.

  • Occupational Exposure

    Historical exposure to chemicals used in dye factories, rubber, leather, and textiles (specifically aromatic amines) is a known risk factor.

  • Chronic Inflammation

    Long-term use of urinary catheters or repeated bladder stones can lead to squamous cell carcinoma.

  • Previous Treatments

    Certain chemotherapy drugs or pelvic radiotherapy for other cancers can increase long-term risk.

The Solution: Treatment pathways

The treatment strategy depends on whether the cancer is non-muscle-invasive (early) or muscle-invasive (advanced).

Diagnostic Pathway

Diagnosis typically begins with a cystoscopy, where a thin camera is passed into the bladder, and a CT scan. If an abnormality is found, further staging is sometimes performed with an MR scan of the bladder area. Usually then a procedure called TURBT (Transurethral Resection of a Bladder Tumour) is performed. This is both a diagnostic tool, providing a biopsy to determine the grade and stage, and often the first step in treatment.

Treatment Options

  • Non-Muscle-Invasive: If the cancer is on the surface lining, the TURBT may remove the tumour entirely. This is often followed by a dose of intravesical chemotherapy (liquid medicine put directly into the bladder) to reduce the risk of return.
  • BCG Therapy: For higher-risk early cancers, an immunotherapy called BCG is used to stimulate the immune system to attack cancer cells in the bladder.
  • Surgery (Cystectomy): If the cancer has invaded the muscle layer, the most effective path may be the surgical removal of the bladder.
  • Systemic Chemotherapy or Radiotherapy: These are used for more advanced stages or to shrink tumours before surgery.
  • Bladder-preserving combinations of TURBT, chemotherapy, radiotherapy.

How to Prevent?

While some risk factors like age cannot be changed, you can take proactive steps to protect your bladder health:

  1. Stop Smoking: This is the single most effective way to lower your risk. Even after years of smoking, quitting significantly reduces the accumulation of toxins in your bladder.
  2. Stay Hydrated: Drinking plenty of water helps to dilute your urine and ensures that any potentially harmful chemicals are flushed out of your system more quickly.
  3. Workplace Safety: If you work in an industry involving chemicals or dyes, strictly follow all health and safety protocols and use personal protective equipment.
  4. Eat a Colourful Diet: Focus on fruits and vegetables rich in antioxidants, which may help protect your cells from DNA damage.
Bladder Cancer: Understanding the Risks, the Signs, and the Strategy

FAQs

If I see blood once and it goes away, do I still need a check-up?

Yes. Bladder cancer is notorious for causing intermittent bleeding. The absence of blood the following day does not mean the underlying cause has resolved.

Is blood in the urine always cancer?

No. It is often caused by UTIs, kidney stones, or an enlarged prostate (BPH). However, because bladder cancer is a possibility, the NHS guidelines state that visible blood must always be investigated by a specialist.

Can a urine test detect bladder cancer?

A urine test can detect microscopic blood that you cannot see with the naked eye. It can also look for abnormal cells (cytology), but a cystoscopy remains the gold standard for a definitive diagnosis. Urinary markers are promising but not widely available.

Why do I need follow-ups for years after treatment?

Early-stage bladder cancer has a high recurrence rate, with around 75 percent of cases returning. Regular check-ups ensure that if it does return, it is caught and treated while it is still manageable.

Does a UTI mean I don’t have cancer?

Not necessarily. While a UTI is a common cause of symptoms, having an infection does not rule out the presence of a tumour and tumours, when present, often cause infection. If symptoms persist after a course of antibiotics, further investigation is essential.

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Prostate Cancer: A Guide to Risk, Diagnosis, and Measured Management https://d.ambeego.com/prostate-cancer/ https://d.ambeego.com/prostate-cancer/#respond Mon, 23 Feb 2026 05:44:02 +0000 https://gerry-collins-urology-wp-tkeapw-d74642-23-88-63-91.traefik.me/?p=2032 Prostate cancer is the most common cancer among men in the UK, with approximately 52,000 new cases diagnosed every year. The prostate is a small gland, roughly the size of a satsuma, located at the base of the bladder. Its primary function is the production of the fluid that nourishes and helps spermatozoa to thrive.. While a diagnosis can be daunting, most prostate cancers are slow-growing and, when detected early, can be managed very effectively, sometimes just with careful observation. In many cases, the cancer remains confined to the prostate gland and may never cause significant harm during a man’s lifetime. However, other types are more aggressive and require prompt, strategic intervention to prevent spread to other parts of the body. Did you know: In the UK, 1 in 8 men will be diagnosed with prostate cancer in their lifetime. This risk increases significantly to 1 in 4 for Black men, highlighting the importance of tailored screening and early awareness within specific risk groups. Symptoms Prostate cancer does not usually cause symptoms until it has spread to other parts of the body; in other words, symptoms are caused by secondaries. Urinary symptoms are usually caused by benign non-cancerous enlargement of the prostate (BPH), which is very common.  The prostate starts to enlarge in the vast majority of men in their 40s. Nevertheless, you should consult a specialist if you notice: In advanced cancer, symptoms might also include persistent back, hip, or pelvis pain, unexplained weight loss, or erectile dysfunction. Causes & Risk Factors While the exact cause of prostate cancer remains unknown, several factors increase the likelihood of development: The Solution: Treatment pathways Management is categorised by risk groups: low, intermediate, and high risk. Treatment is never “one size fits all” and is dictated by the grade of the cancer and the patient’s overall health. Medical & Surveillance Pathways: Surgical & Radical Pathways: How to Prevent? While you cannot change your genetics or age, you can support your prostate health through proactive lifestyle choices: FAQs

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Prostate cancer is the most common cancer among men in the UK, with approximately 52,000 new cases diagnosed every year. The prostate is a small gland, roughly the size of a satsuma, located at the base of the bladder. Its primary function is the production of the fluid that nourishes and helps spermatozoa to thrive.. While a diagnosis can be daunting, most prostate cancers are slow-growing and, when detected early, can be managed very effectively, sometimes just with careful observation.

In many cases, the cancer remains confined to the prostate gland and may never cause significant harm during a man’s lifetime. However, other types are more aggressive and require prompt, strategic intervention to prevent spread to other parts of the body.

Did you know:

In the UK, 1 in 8 men will be diagnosed with prostate cancer in their lifetime. This risk increases significantly to 1 in 4 for Black men, highlighting the importance of tailored screening and early awareness within specific risk groups.

Symptoms

Prostate cancer does not usually cause symptoms until it has spread to other parts of the body; in other words, symptoms are caused by secondaries. Urinary symptoms are usually caused by benign non-cancerous enlargement of the prostate (BPH), which is very common.  The prostate starts to enlarge in the vast majority of men in their 40s.

Nevertheless, you should consult a specialist if you notice:

  • An increased need to urinate, especially during the night (nocturia).
  • Difficulty starting to pee or straining during the process.
  • A weak or interrupted flow of urine.
  • A feeling that your bladder has not fully emptied.
  • Blood in the urine or semen (haematuria).

In advanced cancer, symptoms might also include persistent back, hip, or pelvis pain, unexplained weight loss, or erectile dysfunction.

gerry collins

Mr. Collins Approach

Mr Gerry Collins views every diagnosis as a unique biological puzzle rather than a routine procedure. Having conducted extensive research at Edinburgh University and the Mayo Clinic, his approach is built on “Clinical Discernment.” This means looking beyond raw PSA numbers to understand the individual biology of each patient.

While MR is the current state of the art imaging, there are significant limitations in that MR cannot easily distinguish between cancer and inflammation (common) and therefore even abnormal MRs need to be interpreted before deciding to proceed to biopsy.

Causes & Risk Factors

While the exact cause of prostate cancer remains unknown, several factors increase the likelihood of development:

  • Age

    The risk rises significantly after age 50. Most cases are diagnosed in men aged 65 to 79.

  • Ethnicity

    Black men are at a higher risk of developing the disease and often at a younger age.

  • Family History

    If a close relative (father or brother) had prostate cancer, or if there is a history of BRCA1 or BRCA2 genes (often linked to breast cancer), your risk is higher.

  • Lifestyle Factors

    Obesity and a diet high in animal fats may be linked to more aggressive forms of the disease.

The Solution: Treatment pathways

Management is categorised by risk groups: low, intermediate, and high risk. Treatment is never “one size fits all” and is dictated by the grade of the cancer and the patient’s overall health.

Medical & Surveillance Pathways:

  • Active Surveillance: For low-risk, slow-growing cancers, we monitor the cancer closely with regular PSA tests and scans, avoiding the side effects of surgery or radiation unless the disease shows signs of progressing.
  • Hormone Therapy (ADT): This lowers testosterone levels to shrink the cancer or slow its growth. Mr Collins places a specific emphasis on “Bone Health Optimisation” during this phase to prevent the bone thinning often associated with long-term hormone treatment.

Surgical & Radical Pathways:

  • Radical Prostatectomy: The surgical removal of the prostate gland. Mr Collins brings decades of experience to these complex procedures, focusing on precision and the preservation of quality of life.
  • Radiotherapy & Brachytherapy: Using high-energy beams or internal radioactive “seeds” to destroy cancer cells.

How to Prevent?

While you cannot change your genetics or age, you can support your prostate health through proactive lifestyle choices:

  • Dietary Choices: Incorporate foods rich in lycopene, such as cooked tomatoes, and cruciferous vegetables like broccoli and cauliflower.
  • Maintain a Healthy Weight: Evidence suggests that obesity is linked to more aggressive prostate cancers.
  • Regular Exercise: Staying active improves overall metabolic health and can help manage hormone levels.
  • Smoking Cessation: Smokers may have a higher risk of cancer recurrence and poorer outcomes following treatment.

FAQs

Is a high PSA result always cancer?

No. A raised PSA (Prostate-Specific Antigen) can be caused by an enlarged prostate (BPH), a urinary tract infection, or even recent vigorous exercise. This is why Mr Collins uses PSA density and trends rather than a single figure to make a diagnosis.

If I have no symptoms, do I still need a check-up?

If you are over 50, or over 45 with a family history or Black heritage, a baseline PSA test is highly recommended. Early-stage prostate cancer is frequently silent, and early detection remains the most effective tool for a cure.

Will treatment affect my sex life?

Treatments like surgery or hormone therapy can impact erectile function. However, modern nerve-sparing techniques and rehabilitative therapies are designed to minimise these risks and help men regain function.

What is the Stockholm3 test?

It is an advanced blood test that combines protein biomarkers, genetic markers, and clinical data. It is significantly more accurate than a standard PSA test at detecting aggressive cancers while reducing the need for unnecessary biopsies.

The post Prostate Cancer: A Guide to Risk, Diagnosis, and Measured Management appeared first on Gerry Collins Urology.

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